What Is The Difference Between PGS And PGD?

Dr. Randy Morris

What Is The Difference Between PGS And PGD?

Dr. Randy Morris

Genetic testing is an optional ancillary procedure to a traditional In Vitro Fertilization (IVF) cycle. Genetic testing of embryos in conjunction with IVF benefits all hopeful parents-to-be undergoing infertility treatment. By extracting cells from embryos prior to transfer and implantation into the mother’s uterus, embryos can be screened for genetic disease.


Embryos are screened either through PGD or PGS. These groups of women should seriously consider genetic testing:

  • Women over 35 who are undergoing In Vitro Fertilization (IVF)
  • Women who’ve experienced recurrent miscarriages
  • Women who’ve experienced multiple failed IVF cycles
  • Parents who are known carriers of a genetic disease
  • Parents who have a child with a genetic disease

Performing genetic testing in conjunction with IVF increases the chance of pregnancy and probability of a healthy, full term birth.

Preimplantation Genetic Diagnosis – PGD

Preimplantation Genetic Diagnosis (PGD) – also referred to as preimplantation genetic testing – is screening for other factors, such as the gender of an embryo, in addition to genetic disease. PGD is the process of removing one cell from an embryo developing in vitro for genetic testing. The embryo’s cell is analyzed for the presence of a gene mutation or an unbalanced chromosome. PGD is recommended when one of the parents is known to have a genetic disease history.

Preimplantation Screening – PGS

Preimplantation Screening (PGS) is the process of removing cells from an embryo developing in vitro to be screened for aneuploidy – the condition of having too many or too few chromosomes – evidence of a genetic defect. PGS is recommended for parents whose genes are known or presumed to be chromosomally normal. Humans have 23 pairs of chromosomes. As a women ages, her lower quality of eggs raises the chances of producing an embryo with an abnormal number of chromosomes.

PGS and PGD Specialists

Dr. Randy S. Morris – founder and Medical Director of IVF1 – has been a fertility specialist in the practice of IVF for over 20 years. Since opening IVF1’s brand new, state of the art IVF facility and laboratory in the Naperville Fertility Center, Dr. Morris has experienced a drastic increase in IVF pregnancy success rates. Learn more about how PGS and PGD can improve your chances of giving birth to a healthy, full term baby through IVF.Click the icon below to receive your free eBook Guide To Fertility Treatment compliments of Dr. Randy S. Morris – or – call 630.357.6540 to schedule a consultation.