Project Description

PGD: Blastomere biopsy with three color FISH

In this example, a patient has undergone IVF with PGD to determine if there are abnormalities in the number of chromosomes. The cell pictured here is one cell (blastomere) taken from an eight cell embryo. The embryo itself remains in the carefully guarded conditions of the incubator in the IVF lab. Flourescent in situ hybridization was performed for three chromosomes (Three color FISH): Chromosomes number 13, 18, and 21. These three chromosomes are responsible for a large percentage of failed IVF cycles, miscarriages and can give rise to live born babies with birth defects.