Risks of Metformin Use During Pregnancy
Metformin and Fertility
Metformin has become a popular medication for the treatment of women with PCOS and insulin resistance . Numerous studies have found that some women who don’t ovulate due to PCOS or insulin resistance, may ovulate when using metformin.
Risks of Metformin Use During Pregnancy
A woman who said she is pregnant with a record-breaking 12 babies has been exposed as a fraud, according to reports.
Health officials in the woman’s home country of Tunisia have investigated the claims and concluded that she “has psychological problems and is unlikely to even be pregnant,” Britain’s Daily Telegraphreports.
These days, there is much concern about the swine flu. This particular type of influenza is a new variety. Because Dr. Morris doesn’t have experience or research on this type of the flu, he is relying on the opinion of the Center for Disease Control and Prevention (CDC), whose experts have been studying this infection since its outbreak this spring. […]
Researchers have recently found that professional cyclists should consider the risks involved with the combination of cycling and infertility. In theory, riding a bicycle or motorcycle could cause abnormalities in either sperm concentration, sperm motility or sperm appearance or morphology. […]
An infertility doctor from Ireland presented research at the 25th annual conference of the European Society of Human Reproduction and Embryology in July 2009 that appears to show that IVF success may partly depend on genetic factors. […]
Daily sex (or ejaculating daily) for seven days improves men’s sperm quality by reducing the amount of DNA damage, according to an Australian study presented recently to the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam. This study made headlines around the world. However, there is still no evidence that frequent ejaculation will improve the actual chances to have a baby. […]
Patients who come to a fertility specialist want to become pregnant as soon as possible. There are various treatment options now available for infertility; some have higher pregnancy rates and some have lower pregnancy rates. These treatments have markedly different costs and differing levels of complexity.
Very commonly patients may start with a less effective treatment because it is easier to do or less expensive. It is not unusual to see a couple first try treatment with clomid , perhaps combined with IUI (intrauterine insemination) for three or four attempts. […]
Unfortunately, a significant decline in reproduction success occurs as women get older. This includes poor egg quality, reduction in recruitment of eggs, and a reduction in response to internal and external hormones. In some cases, there have been advances in fertility treatments to compensate for these losses in reproductive success. One commonly used treatment is the use of fertility medications to stimulate multiple egg development (also known as controlled ovarian hyperstimulation (COH)) combined with intrauterine insemination (IUI) . This infertility treatment is often used for unexplained infertility , early stage endometriosis , and mild male factor infertility . […]
Recurrent miscarriage is defined as 3 or more consecutive miscarriages . This condition affects 1% of fertile couples and in 50% of cases, the cause remains undiagnosed. Because of this, it remains one of the most distressing and stressful problems affecting couples trying to conceive.
Recently, it has been suggested that body mass index (BMI) plays a role in the risk of miscarriage in women with recurrent miscarriage.
A study was done in 2009 to determine whether a policy of elective single-embryo transfer (e-SET) in IVF lowers the rate of multiple births (twins, etc.) without compromising the live birth rate. Elective single-embryo transfer (e-SET) is the transfer of one embryo into the uterus during IVF as compared to two.
Yury Verlinsky (09/01/1943- 07/16/2009)
We regret to announce the death on 16th July, 2009 after a period of illness of Dr. Yury Verlinsky, Aged 66.
Dr. Yury Verlinsky, born September 1, 1943, in Siberia, graduated and obtained his PhD in Cytogenetics and Embryologyfrom Kharkov University. He started his research career in genetics in Ukraine already in […]
With an overall prevalence of 3%-5%, babies born with birth defects are the leading cause of infant death in the United States. Down syndrome is the most common chromosomal cause for birth defects. The most common non-chromosomal birth defects are congenital heart defects, cleft lip and palate, and abdominal wall defects (gastroschisis or omphalocele). New data suggests that if a women gives birth between the ages of 25 and 30, then the risk of babies with non-chromosomal birth defects is at its lowest. Women who are both older and younger than this seem to have a greater risk for this type of birth defects. […]
Numerous studies have been done in the past trying to determine the relationship between infertility and some types of cancer in women. Some of these suggest that the fertility medicines used during treatment are responsible for an increased risk in breast and ovarian cancer. Other studies contradict these findings and say that the drugs themselves are not linked to an increased risk of cancer. […]
A study done previously by a Danish recurrent miscarriage clinic observed patients referred from 1986 to 1999 and found that firstborn boys opposed to firstborn girls are far more frequent in mothers with secondary recurrent miscarriage. Also, a firstborn boy was correlated to a less favorable pregnancy potential. In the 14-year follow-up done by the clinic, mothers with firstborn sons had fewer subsequent live births than mothers with firstborn daughters. Approximately 1% of women have what is known as recurrent miscarriage. This means that they have had at least 3 consecutive miscarriages. Of that 1%, approximately 1/3 suffers from secondary recurrent miscarriage, meaning that they have had a child prior to having repeated failed pregnancies. […]
With the changing environment and the continual development of new products with new materials, it is no surprise that people are more worried about their exposure to chemicals than ever. Chemicals are in everything we use. Some of these chemicals can have certain adverse effects on infertility, miscarriage or even the success of treatments such as IVF that have yet to be determined. […]
Women who undergo fertility treatments know how time consuming and sometimes unpredictable the process can be. Because of the need for frequent monitoring, blood checks, and sonograms, working women find their schedules at times hard to manage. It can be very frustrating trying to balance the frequent medical appointments with the stress of their normal daily lives. […]
Several studies have shown a link between female infertility and obesity. Female diabetes has been linked to miscarriage and birth defects. Little data has been published on the effect of male weight and infertility. A new study shows diabetes and being overweight has a negative effect on male fertility.Diabetes is a disease associated with high blood sugar. The body normally produces a hormone called insulin, which regulates blood sugar and keeps it low. People can develop diabetes from a failure to make insulin (Type 1) or resistance to insulin (Type 2). The most common reason that people develop insulin resistance is being overweight or obese.
In the last few decades, a higher percentage of Americans have become overweight. As a result, the rate of diabetes is increasing by a huge amount.
Background Approximately 10-15% of recognized pregnancies end in miscarriage. The main cause of miscarriage is attributed to chromosomal abnormalities in the embryos. Approximately 70-80% of miscarriages occur due to chromosomal defects in the embryo. Unfortunately, as women age, their eggs age as well. The older an egg gets, the greater the chance for chromosomal abnormalities in an embryo formed from that egg. If an embryo has a chromosomal abnormality, there is a much greater chance the pregnancy will end in miscarriage. Less than one percent of chromosomally abnormal fetuses are live born. Chromosomes come in pairs. Each parent contributes half of their child’s genetic makeup. 23 chromosomes are inherited from each parent giving the total of 46. During fertilization, some embryos get one too many of a certain chromosome (trisomy) whereas some embryos may be missing one chromosome (monosomy). These types of abnormalities are known as aneuploidies. The most common form of aneuploidy in humans is Down’s syndrome. Babies with Down’s Syndrome are born with an extra copy of chromosome 21 (trisomy 21). Next to Down’s Syndrome, the most common abnormalities found are trisomy 13 and trisomy 18. Previous research has shown that women who have a live birth of a baby with an aneuploidy such as Down Syndrome are at an increased risk for another baby with the same or different aneuploidy. However, it is not clear if women who has a miscarriage due to an aneuploidy are at higher risk for another baby with an aneuploidy. A study performed recently investigated whether a history of spontaneous miscarriage predicted an increased risk of fetal aneuploidy. […]
Many questions are asked about the freezing of embryos and its effect on pregnancy rates. How long do frozen embryos stay viable? Is there a lesser chance of pregnancy down the road? What effect will freezing embryos have on the fetus? Numerous studies have been performed that prove embryo freezing is safe and effective. The embryos are viable for long periods of time and have produced many successful pregnancies. In fact, a recent study reported at the European Society for Human Reproduction and Embryology discovered that children born from frozen embryos do better and have a higher birth weight than children born from a fresh transfer. […]
For the last 10 years, the techniques of preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) have been used to detect genetic mutations and chromosomal abnormalities in developing embryos. It has been a revolutionary method that has resulted in reductions in the rate of miscarriage and babies with chromosome abnormalities and has accurately identified hundreds of different genetic disorders in the embryos of IVF patients.
As women age, the probability for chromosomal abnormalities increases. PGS involves removing a cell or two from the early stages of a growing embryo and analyzing the number of chromosomes. Normal human embryos contain 23 pairs of chromosomes. Commonly however, embryos will contain too many or too few chromosomes. These abnormalities which are known as aneuploidies, can lead to implantation failure, miscarriage or birth defects such as Down’s syndrome.
PGD involves removing cells from the early embryo to test for genetic mutations which can cause disease.